Risk Factors of 90-Day Unplanned Readmission After Lumbar Spine Surgery for Degenerative Lumbar Disk Disease: A Systematic Review and Meta-Analysis

Neurosurgery 97:908–916, 2025

This meta-analysis identified a 7.72% 90-day unplanned readmission rate after lumbar spine surgery. Significant risk factors include older age, higher BMI, depression, diabetes, hypertension, renal failure, and ASA grade >2. Enhanced preoperative optimization and targeted strategies for high-risk patients are recommended to reduce readmissions.

• A meta-analysis of 11 studies (648,415 patients) found a 7.72% incidence of unplanned 90-day readmission after lumbar spine surgery.

• Significant risk factors for readmission include older age, higher body mass index (BMI), depression, diabetes mellitus (DM), hypertension (HTN), renal failure, and an American Society of Anesthesiologists (ASA) grade greater than 2.

• Surgical factors such as fusion and laminectomy were not significantly associated with readmission.

• Main causes for readmission included wound infection, wound dehiscence, and implant failure; disk reherniation was the leading cause at 90 days.

• Enhanced preoperative optimization and careful patient selection are recommended, especially for elderly and high-comorbidity patients.

• Targeted preventive strategies may reduce readmissions and improve healthcare resource utilization.

• Limitations include retrospective study designs and insufficient data on some perioperative risk factors.

Does Anterior Lumbar Interbody Fusion Reduce Mechanical Complication and Pseudarthrosis Rate at the Lumbosacral Junction in Adult Spinal Deformity Surgery in Comparison to Posterior Lumbar Interbody Fusion?

Int J Spine Surg 2025, 19 (4) 409-417

In adult spinal deformity surgery, anterior lumbar interbody fusion (ALIF) at the lumbosacral junction significantly reduces mechanical complications, pseudarthrosis, and reoperation rates compared to posterior lumbar interbody fusion (PLIF), suggesting ALIF should be preferred unless direct posterior decompression is necessary.

• ALIF (anterior lumbar interbody fusion) at the lumbosacral junction significantly reduces mechanical complications and pseudarthrosis rates compared to PLIF (posterior lumbar interbody fusion) in adult spinal deformity (ASD) surgery.

• ALIF is associated with lower rates of implant-related pain and reoperation than PLIF.

• PLIF is an independent risk factor for mechanical complications in long-segment ASD constructs.

• ALIF results in significantly less blood loss, fewer transfusions, and shorter ICU and hospital stays than PLIF.

• ALIF provides superior biomechanical stability and fusion rates, likely due to better endplate preparation and larger cage footprint.

• PLIF remains suitable for cases requiring direct neural decompression, such as severe stenosis or spondylolisthesis.

• Surgical technique selection should consider patient anatomy, surgical goals, and specific pathology at the lumbosacral junction.

• Study limitations include retrospective design, single-center data, and potential selection bias; further multicenter studies are needed.

Analysis of lumbar plexopathies and nerve injury after lateral retroperitoneal transpsoas approach

Analysis of lumbar plexopathies and nerve injury after lateral retroperitoneal transpsoas approach

DOI: 10.3171/2012.11.SPINE12755

The minimally invasive lateral transpsoas approach has become an increasingly popular means of fusion. The most frequent complication is related to lumbar plexus nerve injuries; these can be diagnosed based on distribution of neurological deficit following the motor and/or sensory nerve injury. However, the literature has failed to provide a clinically relevant description of these complications. With accurate clinical diagnosis, spine practitioners can provide more precise prognostic and management recommendations to include observation, nerve blocks, neurodestructive procedures, medications, or surgical repair strategies. The purpose of this study was to standardize the clinical findings of lumbar plexopathies and nerve injuries associated with minimally invasive lateral retroperitoneal transpsoas lumbar fusion.

Methods. A thorough literature search of the MEDLINE database up to June 2012 was performed to identify studies that reported lumbar plexus and nerve injuries after the minimally invasive lateral retroperitoneal transpsoas approach. Included studies were assessed for described neurological deficits postoperatively. Studies that did attempt to describe nerve-related complications clinically were excluded. A clinically relevant assessment of lumbar plexus nerve injury was derived to standardize early diagnosis and outline prognostic implications.

Results. A total of 18 studies were selected with a total of 2310 patients; 304 patients were reported to have possible plexus-related complications. The incidence of documented nerve and/or root injury and abdominal paresis ranged from 0% to 3.4% and 4.2%, respectively. Motor weakness ranged from 0.7% to 33.6%. Sensory complications ranged from 0% to 75%. A lack of consistency in the descriptions of the lumbar plexopathies and/or nerve injuries as well as a lack of diagnostic paradigms was noted across studies reviewed. Sensory dermal zones were established and a standardized approach was proposed.

Conclusions. There is underreporting of postoperative lumbar plexus nerve injury and a lack of standardization of clinical findings of neural complications related to the minimally invasive lateral retroperitoneal transpsoas approach. The authors provide a diagnostic paradigm that allows for an efficient and accurate classification of postoperative lumbar plexopathies and nerve injuries.