Acta Neurochirurgica (2025) 167:63
The study investigates the relationship between mental fatigue and cognitive functioning in patients with lower-grade gliomas (LGG) before surgery. It found a consistent correlation between self-reported mental fatigue and cognitive functioning but no correlation between self-reports and neuropsychological test results, highlighting the complexity of evaluating these symptoms.
• Study Purpose: Investigate mental fatigue and cognitive functioning in LGG patients pre-surgery.
• Patient Cohort: 101 patients with presumed LGG; 71 with confirmed IDH-mutated LGG.
• Methods: Self-reports, neuropsychological tests, and clinical/demographic data collected.
• Key Findings: No strong correlation between self-reports and neuropsychological tests.
• Correlation: A strong link was found between self-reported mental fatigue and cognitive functioning.
• Tumor Localization: Frontal tumors had more oligodendrogliomas; non-frontal had more glioblastomas.
• Neuropsychological Impairment: Higher RAVLT, FAS, and CWT test impairment rates.
• Statistical Analysis: Spearman’s partial correlations assess variable relationships.
• Clinical Implications: Need for a multi-perspective approach in evaluating LGG patient symptoms.
• Research Recommendations: Larger cohort studies and quantitative tumor localization metrics are suggested.
You must be logged in to post a comment.