J Neurosurg Spine 43:313–323, 2025
In adults with spinal deformity, intradiscal osteotomy (IDO) is as effective as pedicle subtraction osteotomy (PSO) for lordosis restoration and sagittal balance, with similar complication rates but significantly less blood loss, shorter operative time, and less postoperative back pain at 3 months.
• Intradiscal osteotomy (IDO) and pedicle subtraction osteotomy (PSO) are both used to correct adult spinal deformity, aiming to restore lumbar lordosis and sagittal balance.
• IDO and PSO showed similar fusion rates and complication profiles, with no statistically significant difference in rates of proximal junctional kyphosis, hardware failure, DVT, wound infection, or pseudarthrosis.
• IDO resulted in significantly less estimated blood loss (800 ml vs. 1400 ml) and shorter operative time (7 vs. 8.5 hours) compared to PSO.
• IDO patients reported less back pain at 3 months post-op (VAS 1 vs. 3, p=0.01) than PSO patients.
• Both techniques effectively restored lumbar lordosis, but IDO achieved better postoperative sagittal vertical axis (SVA) correction (5 cm vs. 7 cm, p=0.01).
• Higher BMI was a significant risk factor for postoperative complications in both groups.
• IDO is less technically complex, preserves vertebral body integrity, and is more familiar to spine surgeons than PSO.
• IDO can be considered an effective and potentially safer alternative to PSO for selected adult spinal deformity patients.



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