J Neurosurg 143:214–219, 2025
Microsurgical clipping for intracranial aneurysms in patients aged 70 and older showed complication, mortality, and functional dependence rates comparable to younger patients, supporting its safety and efficacy in selected elderly individuals. Careful patient selection remains crucial; further studies are encouraged to confirm these findings.
• Microsurgical clipping for intracranial aneurysms in elderly patients (≥70 years) shows outcomes comparable to those in younger patients (<70 years).
• A retrospective single-center study (2016–2022) matched 50 elderly with 100 younger patients using propensity score matching.
• No significant differences were found between age groups for complications, extended length of stay, nonhome discharge, functional dependence, or mortality.
• Aneurysm characteristics (location, morphology, rupture status) were similar between groups.
• Frailty and comorbidities, rather than age alone, are important predictors of outcomes after clipping.
• Study highlights the safety of microsurgical clipping in well-selected elderly patients, but emphasizes careful patient selection.
• Limitations include single-center design, possible selection bias, and influence of unmeasured confounders.
• Further research is needed to validate findings and guide patient selection for clipping in the elderly.
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