J Neurosurg Spine 43:195–204, 2025
This 10-year retrospective study found that cervical disc arthroplasty (CDA) provides sustained clinical improvement and preserves segmental mobility, with the Bryan disc maintaining greater range of motion than the Prestige LP. However, high rates of heterotopic ossification (69.2%) and adjacent segment degeneration (55.4%) were observed.
• Retrospective single-center study of 74 patients (91 levels) undergoing Bryan or Prestige LP cervical disc arthroplasty (CDA) between 2004–2013, with minimum 10-year follow-up.
• Significant long-term improvement in clinical outcomes (JOA, NDI, VAS) maintained at 10 years postoperatively.
• No significant clinical outcome differences between Bryan and Prestige LP groups at any follow-up point.
• Bryan disc group had significantly higher global and segmental range of motion (ROM) than Prestige LP group at 10 years.
• High rates of radiological complications: heterotopic ossification (HO) in 69.2% (29.7% ROM-limiting), adjacent segment degeneration (ASD) in 55.4%, segmental kyphosis in 11% overall.
• No patients required reoperation during follow-up.
• Older age was a significant risk factor for ASD; no significant risk factors identified for HO.
• CDA provides satisfactory long-term clinical outcomes and preserves segmental mobility, but HO and ASD are common and require ongoing attention
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