Category: Spine

Posted on

Surgical outcomes of unilateral painful foot drop secondary to lumbar disc herniation

J Neurosurg Spine 42:727–736, 2025

This multicenter retrospective study of 75 patients found that prompt surgical intervention for unilateral painful foot drop due to lumbar disc herniation improves outcomes, especially in younger and less frail patients. Delays in surgery reduced the likelihood of recovery, but no specific timing cutoff was identified.

• This multicenter retrospective study analyzed surgical outcomes for unilateral painful foot drop caused by lumbar disc herniation, excluding cauda equina syndrome cases.

• 75 adult patients were included; improvement in muscle strength (MRC grade) was seen in 55%, with 23% achieving full resolution of foot drop.

• Earlier surgery, younger age, and lower frailty scores were associated with better outcomes; for each day surgery was delayed, chance of improvement dropped by 0.2%.

• No specific surgical timing cutoff was identified, but delays reduced likelihood of recovery.

• Patients with more severe initial weakness (lower MRC grade) were more likely to show some improvement, but less likely to achieve full resolution.

• Radicular pain (sciatica) improved in most patients regardless of time to surgery.

• Study limitations include small sample size, retrospective design, and variability between centers.

• Authors recommend early surgical consideration and call for larger prospective studies to refine guidelines.

Posted on

Technique and outcomes of the trans-superior articular process approach for endoscopic thoracic discectomy

J Neurosurg Spine 42:775–783, 2025

The trans-superior articular process (SAP) approach for endoscopic thoracic discectomy enables safe, minimally invasive treatment of symptomatic thoracic disc herniation, particularly in challenging upper/mid-thoracic regions, with significant improvements in pain and disability, short operative time, and low complication rates in a 38-patient series.

• Trans-superior articular process (trans-SAP) approach for endoscopic thoracic discectomy is described for symptomatic thoracic disc herniation (TDH).

• This technique creates a controlled corridor through the SAP using a Jamshidi needle and manual bone drills, minimizing facet removal and neural injury.

• Study included 38 patients (mean age 48.9), mostly with central or middle thoracic herniations.

• Mean operative time was 42 minutes, hospital stay 1.3 days, and follow-up 11.5 months.

• Significant improvements in pain (VAS) and disability (ODI) scores were observed at all follow-up points.

• Only one complication (2.6%, recurrent herniation) was reported.

• Trans-SAP approach is safe, effective, and minimally invasive, but has a steep learning curve and is not suitable for hard disc, severe myelopathy, or ossified ligament cases.

• Technique enables treatment of central and paramedian TDH and can be performed under local anesthesia.

Posted on

Factors associated with cervical instability in cervical myelopathy patients

J Neurosurg Spine 42:673–678, 2025

This study found a high prevalence (43.1%) of cervical instability in patients with cervical spondylotic myelopathy (CSM). Key factors associated with instability included cervical facet joint degeneration, increased T1 slope minus cervical lordosis (T1S−CL), and higher neck pain scores.

• Cervical instability is common in patients with cervical spondylotic myelopathy (CSM), with a prevalence of 43.1%.

• Instability was defined as ≥3-mm translational motion between adjacent vertebrae on flexion-extension radiographs.

• Key factors independently associated with cervical instability are higher cervical facet joint degeneration (FJD) scores, increased T1 slope minus cervical lordosis (T1S−CL), and higher visual analog scale (VAS) scores for neck pain.

• Age, sex, BMI, JOA score, and cervical range of motion were not significantly associated with instability.

• Facet joint degeneration plays a critical role in cervical instability, creating a cycle of degeneration and abnormal motion.

• Proper assessment of T1S−CL and FJD is essential for surgical decision-making in CSM patients.

• Study limitations include single-center design, moderate sample size, and exclusion of certain patient groups.

• Spine surgeons should pay special attention to these factors when determining treatment strategies for CSM.

Posted on

Comparison of outcomes between cervical disc arthroplasty and anterior cervical discectomy and fusion for the treatment of cervical spondylotic myelopathy

J Neurosurg Spine 42:705–717, 2025

This systematic review and meta-analysis evaluates the outcomes of cervical disc arthroplasty (CDA) versus anterior cervical discectomy and fusion (ACDF) in treating cervical spondylotic myelopathy (CSM). Based on 12 randomized controlled trials including 2,612 patients, the study found that CDA shows superior clinical effectiveness and a more favorable safety profile than ACDF. Neck pain improvement (VAS) with CDA was clinically meaningful within the first postoperative year. CDA also had lower reoperation rates and reduced incidence of adjacent segment disease (ASD), although with slightly longer operative times. Further high-quality, large-scale trials are needed to confirm these findings.
Key Points
• • Objective: Compare the efficacy and safety of CDA vs. ACDF in CSM patients through meta-analysis.
• • Methods: 12 RCTs with 2,612 patients (1,464 CDA, 1,148 ACDF); outcomes included NDI, VAS, ROM, SF-36, complications, and reoperations.
• • Overall success: Higher in CDA group (RR 1.21; p = 0.004).
• • Neck pain (VAS): Significantly improved in CDA up to 12 months post-op; clinically meaningful.
• • Arm pain (VAS): Slight improvement at 3 and 12 months; not clinically significant.
• • NDI scores: Statistically better in CDA, though often below MCID thresholds.
• • ROM: Better preserved in CDA; data limited and heterogeneous.
• • Quality of life (SF-36): No significant differences between groups.
• • Operative time: Longer in CDA (MD 18.75 min; p < 0.00001).
• • Complications: Similar blood loss and adverse event rates; lower ASD and reoperation rates in CDA.
• • Limitations: Limited CSM-specific data, inconsistent surgical protocols, and risk of bias in several trials.
• • Conclusion: CDA offers better early clinical outcomes and fewer mechanical complications than ACDF, but broader validation is needed.

Posted on

Spinal Anesthesia for Multilevel Awake Minimally Invasive Transforaminal Lumbar Interbody Fusion

Operative Neurosurgery 28:855–861, 2025

This retrospective study found that multilevel awake minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) under spinal anesthesia is safe and effective, with minimal blood loss, good pain control, and short hospital stays, supporting its use even in complex cases for improved patient outcomes.

• Multilevel awake minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) under spinal anesthesia is safe and effective for complex lumbar spine cases.

• A retrospective review of 16 patients (mostly two-level procedures) showed no new neurological deficits and all were discharged home without complications.

• Median age was 69.5 years; common comorbidities included hypertension, obesity, and sleep apnea.

• Median operative time was 156 minutes, with low median blood loss (50 mL) and a median hospital stay of 2 days.

• Postoperative pain was well controlled, most commonly using methocarbamol and short-duration opioids.

• 93.75% of patients reported significant symptomatic improvement at follow-up.

• Awake MIS-TLIF offers benefits over general anesthesia, such as faster recovery, shorter hospital stays, and fewer side effects.

• Study limitations include small sample size and retrospective design; further research is needed.

Posted on

Historical evolution, management, and outcome of surgical treatment for high-grade spondylolisthesis

J Neurosurg Spine 42:784–796, 2025

This systematic review analyzes the evolution and outcomes of surgical techniques for high-grade spondylolisthesis (HGSL). Both reduction and in situ fusion are effective, but reduction carries higher neurological risk and in situ fusion higher nonunion risk. Larger, high-quality studies are needed to guide optimal patient-specific treatment.

• High-grade spondylolisthesis (HGSL) is defined as vertebral slippage >50% (Meyerding grade 3–5) and is rare, with no consensus on optimal surgical management.

• Surgical approaches are divided into reduction and fusion versus in situ fusion, with no gold-standard technique established.

• Reduction techniques are linked to more neurological complications, while in situ fusion (especially older techniques like Bohlman’s) has higher rates of nonunion and graft failure.

• Modifications using transsacral transvertebral screws and titanium cages have reduced nonunion and graft failure rates in in situ fusion.

• Most patients, regardless of technique, report good postoperative outcomes in pain and function.

• Choice of technique should be individualized, considering factors like sacropelvic orientation, pelvic balance, slip angle, and dysplastic features.

• Current evidence is limited to small, heterogeneous case series and reports; no prospective studies exist.

• Larger, well-designed prospective studies are strongly recommended before widespread recommendations can be made.

Posted on

Cost and operating room time savings with single-position prone lateral lumbar interbody circumferential fusion

J Neurosurg Spine 42:768–774, 2025

Single-position prone lateral lumbar interbody fusion (LLIF+PPS) reduces operating room time and costs compared to dual-position surgery, especially for 2-level fusions, while maintaining similar hospital stays and clinical outcomes. Cost savings are most significant in complex, multilevel cases due to eliminated patient repositioning.

• Single-position (SP) prone lateral lumbar interbody fusion (LLIF) eliminates patient repositioning compared to dual-position (DP) LLIF+PPS.

• Study compared costs, operating room (OR) time, and hospital stay between SP and DP LLIF+PPS for 1- and 2-level fusions.

• For 2-level fusions, SP surgery had significantly shorter OR time, lower OR and anesthesiology costs than DP surgery.

• For 1-level fusions, differences in OR time and costs between SP and DP were not statistically significant.

• Hospital length of stay was similar between SP and DP groups for both 1- and 2-level fusions.

• Both approaches showed similar safety, fusion rates, and patient-reported outcomes after at least 1 year.

• SP prone LLIF+PPS is most beneficial for complex, multi-level cases, offering efficiency and cost savings.

• Further studies with larger cohorts are needed to confirm these findings.

Posted on

The Effect of Transpedicular Injection of Recombinant Human Bone Morphogenetic Protein-2/Beta-Tricalcium Phosphate Carrier on the Prevention of Proximal Junctional Kyphosis in Adult Spinal Deformity Surgery: A Pilot Study

Neurosurgery 96:986–996, 2025

The study explores the use of recombinant human bone morphogenetic protein-2 (rhBMP-2) with beta-tricalcium phosphate (β-TCP) to prevent proximal junctional kyphosis (PJK) in adult spinal deformity surgery. Results indicate reduced PJK incidence and increased bone density at the upper instrumented vertebra.

• The study explores the use of transpedicular injection of recombinant human bone morphogenetic protein-2 (rhBMP-2) with a beta-tricalcium phosphate (β-TCP) carrier to prevent proximal junctional kyphosis (PJK) in adult spinal deformity (ASD) surgery.

• 25 patients received rhBMP-2 injections, and their outcomes were compared with two control groups with 66 and 63 patients each.

• Results showed a significantly lower incidence of PJK in the rhBMP-2 group compared to control groups.

• The injection also led to a significant increase in trabecular bone density at the upper instrumented vertebra (UIV).

• Multivariate analysis indicated that rhBMP-2 injection at the UIV had a protective effect against PJK.

• The study suggests that this method can be easily integrated into surgical procedures to enhance bone density and reduce PJK risk.

• Limitations include the small sample size and lack of randomization, warranting further studies.

• The study concludes that rhBMP-2/β-TCP injection is a promising strategy for preventing PJK in ASD surgery.

Posted on

Minimally invasive surgical decompression for lumbosacral extraforaminal stenosis (Far-Out Syndrome)

Acta Neurochirurgica (2025) 167:139

The document discusses a minimally invasive surgical technique for decompressing lumbosacral extraforaminal stenosis, known as “far-out syndrome,” focusing on the L5 nerve root. It highlights the procedure, indications, potential complications, and the importance of specific imaging techniques for accurate diagnosis and effective treatment.

• The study focuses on minimally invasive surgical decompression for lumbosacral extraforaminal stenosis, known as “far-out syndrome”.

• Accurate diagnosis is challenging due to unique anatomical characteristics, requiring oblique coronal MR imaging for detection.

• The procedure involves a paraspinal approach using a tubular retractor to decompress the L5 nerve root.

• Adequate decompression requires the resection of the L5 lower vertebral body bony spur, transverse process, and sacral ala.

• Key surgical landmarks include the transverse process, sacral ala, and superior articular process, which are drilled to relieve nerve compression.

• Common symptoms include unilateral leg pain, weakness, and neurogenic claudication, often presenting unilaterally.

• Surgical indications involve unilateral radiating leg pain resistant to conservative management and MRI evidence of extraforaminal compression.

• Complications can be avoided by ensuring adequate decompression and removing ventral bony spurs.

Posted on

Sarcopenia Predicts the Development of Early Adjacent Segment Disease After Transforaminal Lumbar Interbody Fusion

Neurosurgery 96:1044–1053, 2025

This study explores whether sarcopenia, measured by psoas morphometrics, predicts early adjacent segment disease (ASD) after transforaminal lumbar interbody fusion (TLIF). Results indicate that decreased psoas area and P:VBR are strong predictors of ASD within three years post-surgery, suggesting implications for surgical decision-making and patient counseling.

• Sarcopenia predicts early adjacent segment disease (ASD) after transforaminal lumbar interbody fusion (TLIF) surgery, as shown by decreased psoas area and P:VBR ratios.

• A retrospective study of 109 patients found that 22 (20.2%) developed ASD within 3 years post-surgery.

• Sarcopenic patients had significantly higher rates of ASD (83.33%) compared to nonsarcopenic patients (7.69%).

• Older age, diabetes, and preoperative ODI are significant predictors of ASD.

• Sarcopenia is a stronger predictor of ASD than spinopelvic parameters like PT, LL, and PI-LL mismatch.

• Identifying sarcopenic patients can guide surgical decisions and postoperative care to prevent ASD.

• The study suggests using psoas morphometrics as a simple tool to identify patients at risk for ASD.

• Further research is needed to validate findings and explore the role of sarcopenia in other surgical approaches.

Posted on

Buttock pain in lumbar disc herniation: clinical characteristics, risk factors, and surgical outcomes

J Neurosurg Spine 42:572–578, 2025

The study investigates buttock pain in patients with lumbar disc herniation (LDH), identifying it as a common, independent symptom. It found that buttock pain is associated with contained herniation and an intact annulus fibrosus, and can be effectively treated with endoscopic discectomy.

• Buttock pain is common in patients with lumbar disc herniation (LDH), particularly in the L3–S1 segments, and is often independent of back and leg pain.

• The study examined 321 patients with single-level LDH who underwent endoscopic discectomy, finding that 75.4% experienced buttock pain.

• Buttock pain is more prevalent in patients with contained LDH and an intact annulus fibrosus.

• Endoscopic discectomy is effective in treating buttock pain, with significant improvements observed shortly after surgery and at the 1-year follow-up.

• The occurrence of buttock pain is not associated with age, sex, or specific spinal levels, indicating it as an independent symptom.

• The study suggests that altered intradiscal pressure may be a pathogenic factor for buttock pain in contained LDH.

• Residual buttock pain was more likely in L3–4 LDH, though the sample size for this segment was limited.

Posted on

Management strategies for cervical schwannomas: a comprehensive review

J Neurosurg Spine 42:650–658, 2025

The review discusses cervical schwannomas, focusing on their pathophysiology, clinical presentation, and management strategies, including surgical resection and stereotactic body radiation therapy (SBRT). It emphasizes the importance of a multidisciplinary approach for optimal patient outcomes and highlights the need for ongoing research.

• Cervical schwannomas are benign tumors originating from Schwann cells, often occurring in the intradural, extramedullary space of the cervical spine.

• MRI is the primary imaging modality for diagnosing schwannomas, characterized by avid Gd uptake and specific radiographic features.

• Surgical resection is the main treatment approach, with gross-total resection preferred to minimize recurrence. Various surgical techniques are available depending on tumor location.

• Stereotactic body radiation therapy (SBRT) is a viable alternative for patients who are not surgical candidates, offering good local control and symptomatic relief.

• Histological analysis distinguishes schwannomas through specific features such as Antoni A and B areas and Verocay bodies. Immunohistochemical stains like S100 and SOX10 aid in diagnosis.

• Multidisciplinary management is crucial, integrating surgical and nonsurgical options to optimize patient outcomes and quality of life.

• Observation may be suitable for asymptomatic patients with slow-growing lesions, with regular monitoring to assess progression.

• Malignant transformation into peripheral nerve sheath tumors is rare but possible, particularly in patients with NF1.

Posted on

Development of a unified and comprehensive definition of successful spinal fusion: a systematic review

J Neurosurg Spine 42:403–412, 2025

The document discusses a systematic review aimed at creating a unified definition of successful spinal fusion by integrating clinical symptoms, imaging modalities, and bone healing processes. It proposes a clinical algorithm for evaluating fusion success, emphasizing the need for standardized assessment criteria.

• A systematic review was conducted to develop a unified definition of successful spinal fusion, incorporating clinical symptoms and imaging modalities.

• The review involved 20 studies evaluating 1,324 spinal fusion procedures, resulting in a clinical algorithm for determining fusion success.

• The algorithm stratifies patients as symptomatic or asymptomatic, using specific imaging techniques based on pain type.

• Successful fusion for asymptomatic patients is considered after 12 months, while persistent symptoms indicate failure regardless of radiographic findings.

• Limitations include reliance on imaging and heterogeneous study data, but the algorithm aims to standardize fusion evaluation and improve outcomes.

• Future directions suggest using AI and machine learning for predictive algorithms and evaluating regional differences in fusion assessment.

• The proposed algorithm aims to improve diagnostic accuracy and provide a shared understanding of successful spinal fusion among clinicians.

• Implementation of the algorithm can enhance outcomes research and assess new developments in spinal fusion.

Posted on

Clinical and radiographic comparison of robot-assisted single-position versus traditional dual-position lateral lumbar interbody fusion

J Neurosurg Spine 42:443–452, 2025

The study compares robot-assisted single-position (RA-SP) and traditional dual-position (DP) lateral lumbar interbody fusion (LLIF) surgeries, finding RA-SP-LLIF reduces operative and fluoroscopy times with similar clinical and radiographic outcomes, suggesting enhanced surgical efficiency and safety.

• The study compares robot-assisted single-position (RA-SP) lateral lumbar interbody fusion (LLIF) with traditional dual-position LLIF in terms of clinical and radiographic outcomes.

• 59 patients were analyzed, with 31 undergoing RA-SP-LLIF and 28 undergoing traditional LLIF. Surgical parameters like operative duration, blood loss, and fluoroscopy duration were recorded.

• No significant differences were found in postoperative and follow-up times between groups, but both showed improvements in clinical scores such as VAS, ODI, and SF-36.

• RA-SP-LLIF showed significantly greater improvements in lumbar lordosis and segmental lordosis immediately postoperatively, although these differences were not significant at later evaluations.

• The RA-SP-LLIF group had shorter operative and fluoroscopy durations compared to the traditional LLIF group.

• RA-SP-LLIF is considered a promising technique for enhancing surgical efficiency, safety, and precision in lumbar spinal fusion procedures.

• Both procedures improved sagittal alignment parameters, but RA-SP-LLIF reduced surgery and anesthesia times by eliminating the need for repositioning.

Posted on

Comparative Efficacy and Safety of Endovascular Versus Surgical Treatment in Spinal Dural Arteriovenous Fistulas A Systematic Review and Meta-analysis

Spine 2025;50:562–574

This systematic review and meta-analysis reveal that surgical treatment for spinal dural arteriovenous fistulas (SDAVFs) achieves higher rates of complete occlusion and successful treatment compared to endovascular approaches, with lower recurrence and retreatment rates, despite similar neurological improvements and periprocedural complications.

• Objective: Compare the efficacy and safety of surgical vs. endovascular treatments for spinal dural arteriovenous fistulas (SDAVFs) through a systematic review and meta-analysis.

• Methods: Searched PubMed, Scopus, and Web of Science databases until July 2024, identifying 1192 articles, with 40 studies meeting inclusion criteria, involving 1818 patients.

• Results: Surgical treatment showed higher rates of complete occlusion (96.8%) and successful treatment (97.5%) compared to endovascular treatment (72.5% and 66.7%, respectively).

• Recurrence and Retreatment: Lower rates in the surgical group, with endovascular treatment showing higher initial treatment failure.

• Neurological Improvement: Both treatments had similar improvements in neurological status and periprocedural complications, but surgery showed greater improvement in the ALS score.

• Conclusion: Surgical treatment is preferred for definitive results in SDAVFs, but decisions should be individualized based on patient-specific factors. Further research is needed.

• Limitations: Potential publication bias and heterogeneity among included studies.

• Key Insight: This study is the most updated and comprehensive meta-analysis on SDAVF treatments, providing valuable insights for clinical and policy decisions.

Posted on

Clinical Outcomes and Radiographic Results of Prone Transpsoas Lateral Lumbar Interbody Fusion

Neurosurgery 96:763–768, 2025

The study evaluates the prone transpsoas (PTP) approach for lateral lumbar interbody fusion, showing improved lumbar lordosis, reduced complications, and enhanced patient-reported outcomes. Conducted on 106 patients, the approach minimized operative time and demonstrated safety and efficacy in lumbar fusion.

Clinical Research Summary

• Study Focus: Prone transpsoas lateral lumbar interbody fusion (PTP) for lumbar fusion.

• Study Design: Retrospective observational study of 106 patients, single-surgeon series.

• Patient Demographics: Mean age 66 years, mean BMI 29.3, follow-up 13 months.

• Surgical Technique: Prone positioning, single-position access to anterior/posterior lumbar spine.

• Common Levels: The most common level treated was L4-5.

• Outcomes: Improved lumbar lordosis, reduced pelvic tilt, and decreased PI-LL mismatch.

• Complications: Minimal, with transient hip flexor weakness in 0.9% of patients.

• Pain Scores: VAS pain scores improved from 6 to 5 postoperatively.

• Surgical Indications: Degenerative scoliosis, spondylolisthesis, disk disease, adjacent segment disease, pseudoarthrosis.

• Adverse Events: No bowel or major vessel injuries were reported.

• Radiographic Results: Significant improvement in lumbar lordosis and pelvic parameters.

• Limitations: Single-surgeon study, short follow-up, retrospective data collection.

• Conclusion: PTP approach is safe and effective for lumbar fusion with minimal complications.

Posted on

How to Reduce the Risk of Mechanical Failures in Adult Deformity Surgery: Comparing GAP Score and Roussouly Type Restoration

Global Spine Journal 2025, Vol. 0(0) 1–15

DOI: 10.1177/21925682251328285

This study investigates the predictors of mechanical failure in adult spinal deformity surgery, highlighting the significance of the GAP score and Roussouly type restoration in minimizing complications. A proper post-operative GAP Score and spinal alignment restoration are crucial for reducing mechanical failure rates.

Study Design and Methods

• Retrospective cohort study with a 5-year follow-up on adult spinal deformity cases.

• Inclusion criteria: Patients over 18, with at least 4 vertebrae fused.

• Data collected: Demographic, surgical, spinopelvic parameters, and complications.

Key Findings

• Mechanical Complications: Revision surgery rate was 40.6%.

• Higher post-operative GAP scores linked to increased junctional failure risk.

• Roussouly Type Restoration: Failure to restore original type increases mechanical failure risk.

Predictive Analysis

• GAP Score and Roussouly Type are top predictors for mechanical failure.

• Gradient Boosting model showed high predictive accuracy (ASE 0.073).

• Kaplan-Meier Analysis: Higher GAP scores linked to earlier junctional failures.

Recommendations

• Surgical Planning: Restore original Roussouly type and achieve proper lumbar lordosis.

• Avoid Pelvic Retroversion: Ensure proper global balance.

Statistical Analysis

• Logistic regression confirmed GAP score and Roussouly type as significant predictors.

• ROC Curves: Moderate association between GAP score and revision surgery need.

Limitations

• Retrospective design with potential selection bias.

• Asymmetrical sample size of GAP score groups.

Level of Evidence

3 retrospective cohort study

Posted on

The gap between surgeon goal and achieved sagittal alignment in adult cervical spine deformity surgery

J Neurosurg Spine 42:309–319, 2025

This study assessed surgeons’ ability to achieve preoperative sagittal alignment goals in adult cervical spine deformity surgeries. Results showed significant deviations from targets, especially in severe deformities, highlighting the need for improved surgical planning and personalized implants.

Study Overview

• Objective: Assess surgeons’ ability to achieve preoperative sagittal alignment goals in CSD surgery.

• Methods: Prospective study with adult CSD patients across 13 North American centers.

• Patient Demographics: Mean age 63.6 years; 51.1% women; 38.6% had previous cervical fusion.

Key Findings

• Alignment Goals: Surgeons failed to meet goals by 17.2 mm for C2–7 SVA, 10.3° for Cobb angle.

• Factors Affecting Outcomes: Greater baseline TK linked to better Cobb angle achievement.

• Surgical Planning: 60% used PACS, 33.3% used spine-specific software.

• Tools and Criteria: Ames/ISSG criteria used by 33.3% of surgeons; others individualized goals.

Challenges and Recommendations

• Severe Deformities: More challenging to achieve alignment goals in severe cases.

• Need for Advancements: Personalized implants could improve intraoperative goal achievement.

• Alignment Correlations: Strong correlation for C7–S1 SVA, weak for C2–7 SVA.

Statistical Analysis

• Offset Groups: Patients categorized by offset magnitude from goal alignment.

• Significant Associations: Lower baseline TS-CL associated with better TS-CL goal achievement.

Posted on

Microsurgical Repair of Ventral Cerebrospinal Fluid Leaks in Spontaneous Intracranial Hypotension: Efficacy and Safety of Patch-Sealing Versus Suturing

 

Operative Neurosurgery 28:379–385, 2025

This study compares microsurgical suturing and patch-sealing techniques for repairing ventral cerebrospinal fluid leaks in spontaneous intracranial hypotension. Both methods are equally effective, but sealing is faster and involves less spinal cord manipulation, potentially reducing surgical complications.

Study Overview and Methods

• Compared microsurgical suture vs. patch-sealing for ventral dural leaks in SIH patients.

• Retrospective analysis conducted between 2013 and 2023 at a single center.

• 85 patients with Type 1 SIH leaks were included in the study.

Results

• No significant difference in headache resolution between techniques (89% vs 94%).

• Sealing technique was significantly faster than suturing (139 vs 169 minutes).

• Complication rates: 23% in suture group, 9% in sealing group (not statistically significant).

Clinical Outcomes

• No significant difference in postoperative Bern-Score between techniques.

• SLEC-positive postoperative rate: 13% in suture group, 22% in sealing group.

• 90% of patients reported headache improvement post-surgery.

Discussion

• Both techniques are effective, but sealing minimizes spinal cord manipulation.

• Sealing preferred due to faster surgery time and fewer complications.

• Limitations include retrospective design and potential selection bias.

Posted on

Outcomes After Definitive Surgery for Spinal and Sacral Chordoma in 101 Patients Over 20 Years

Neurosurgery 96:494–504, 2025

• Study Objective: Investigate postoperative outcomes of spinal chordoma surgery over 20 years.

• Patient Cohort: 101 patients, average follow-up of 6.0 ± 4.2 years.

• Recurrence and Mortality: 24.8% recurrence, 9.9% mortality.

• Risk Factors: Tumors ≥100 cm³ and mobile spine chordomas linked to worse outcomes.

• Neoadjuvant Radiotherapy: Associated with improved local recurrence-free survival (LRFS).

• Age Impact: Patients ≥65 years at surgery have a higher mortality risk.

• Surgical Outcomes: Pain decreased post-surgery, sensory deficits and weakness remained static.

• Functional Outcomes: 39% of patients pain-free long-term, no significant change in sensory deficits.

• Surgical Complications: 65.3% experienced complications; 32.7% required reoperation.

• Radiotherapy Advances: Newer modalities like stereotactic photon therapy show promising LRFS rates.

• Study Design: Retrospective review from 2003-2023 at a quaternary spinal oncology center.

• Data Analysis: Multivariable Cox regression used to identify predictors of LRFS and OS.

• Surgical Approach: Enneking Appropriate surgery preferred for better outcomes.

Proudly powered by WordPress