Wartime penetrating traumatic brain injury of the anterior skull base involving the paranasal sinuses: a single-center, first-year experience from Dnipro, Ukraine

J Neurosurg 142:829–838, 2025

Study Focus: The study explores wartime penetrating traumatic brain injuries (pTBIs) involving the anterior skull base and paranasal sinuses during the first year of the Russian-Ukrainian war.

Objective: To identify factors associated with favorable short-term outcomes and survival in patients with pTBIs.

Methodology: A single-center retrospective review was conducted on patients treated at Mechnikov Dnipropetrovsk Regional Clinical Hospital in Ukraine.

Key Findings: High Glasgow Coma Scale (GCS) scores, favorable injury lateralization, and low Injury Severity Scores (ISS) were linked to better short-term outcomes.

Treatment Protocol: The study implemented early primary neurosurgical treatment, including debridement and skull base reconstruction, which showed promising early results.

Patient Outcomes: 84% of patients achieved a favorable outcome, with low rates of postoperative complications like CSF leaks and infections.

Comparison with Other Conflicts: The study highlights differences in management strategies compared to US military experiences in Iraq and Afghanistan.

Limitations: The study lacks a direct comparison group and long-term outcomes are not available due to follow-up challenges.