WORLD NEUROSURGERY 104: 89-94, AUGUST 2017
Unruptured paraclinoid aneurysms are often asymptomatic, and endovascular coiling is the main treatment. However, endovascular treatment of these lesions still leads to neurologic complications. We aimed to identify predictors of neurologic complications in these lesions.
METHODS: We retrospectively analyzed patients with unruptured paraclinoid aneurysms who were treated with endovascular coiling between January 2014 and December 2015. A neurologic complication was defined as any transient or permanent increase in the modified Rankin Scale score after aneurysm embolization. Univariate and mulitivariate logistic regression analyses were performed to assess the risk factors of neurologic complications.
RESULTS: Of the 443 unruptured paraclinoid aneurysms that were included in this study, the incidence of neurologic complications was 5.2%. Neurologic complications were highly correlated with hypertension (odds ratio [OR], 3.147; 95% confidence interval [CI], 1.217e8.138; P [ 0.018), cerebral ischemic comorbidities (OR, 3.396; 95% CI, 1.378e 8.374; P [ 0.008), and aneurysm size (OR, 7.714; 95% CI, 1.784e31.635; P < 0.001), and irregular shape (OR, 3.157; 95% CI, 1.239e8.043; P [ 0.016) in the univariate analysis. Cerebral ischemic comorbidities (OR, 2.837, 95% CI, 1.070e 7.523; P [ 0.036) and aneurysm size as dichotomous variables (OR, 7.557; 95% CI, 2.975e19.198; P < 0.001) were strongly correlated with neurologic complications in the final adjusted multivariate logistic analysis.
CONCLUSIONS: Unruptured paraclinoid aneurysms after endovascular treatments had 5.2% of neurologic complications. Cerebral ischemic comorbidities and aneurysm size were predictors of neurologic complications.
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