Neurosurgery 96:346–355, 2025
Study Overview
• Focus: Brain AVM during pregnancy and puerperium.
• Method: Retrospective cohort study in Finland from 1987 to 2016.
• Data Sources: National Hospital Discharge Register, Medical Birth Register, and AVM registry.
Key Findings
• AVM Rupture: Occurred mostly in the second and third trimesters.
• Previous Pregnancies: Most women with AVM rupture had previous pregnancies.
• Treatment Timing: 35.7% received treatment during pregnancy or puerperium.
• Outcomes: No significant difference between treated and conservatively managed mothers.
Maternal and Fetal Outcomes
• Maternal Mortality: Last AVM-related fatality during pregnancy was in 1988.
• Newborn Health: Most had favorable outcomes, with Apgar scores similar between groups.
• Delivery: Average gestation at delivery was 38 weeks.
Clinical Implications
• Management: Multidisciplinary approach recommended for AVM treatment during pregnancy.
• Research Needs: More studies needed on AVM rupture risk related to delivery method.
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