Acta Neurochirurgica (2025) 167:159
The study found that using a semi-sitting position (30° head elevation) during stereotactic brain biopsies significantly reduced the rate of hemorrhagic complications compared to the supine position, suggesting patient positioning is a key, modifiable factor for improving safety and outcomes in these neurosurgical procedures.
• Study compared bleeding rates in stereotactic brain biopsies between semi-sitting and supine positions.
• Retrospective analysis of 78 patients: 39 semi-sitting, 39 supine.
• Hemorrhagic complications were significantly lower in the semi-sitting group (7.7%) vs supine (33.3%).
• Semi-sitting position is a potential protective factor against bleeding (OR 0.17, p=0.009).
• Groups were similar in age, sex, tumor type, and biopsy site; more samples were taken in semi-sitting group.
• No symptomatic bleedings occurred in either group.
• Semi-sitting position may reduce intracranial venous pressure, lowering bleeding risk.
• Authors recommend further prospective, multicenter studies to validate findings.
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